January 2024
PtuA and PtuB assemble into an inflammasome-like oligomer for anti-phage defense.
Li Y, Shen Z, Zhang M, Yang XY, Cleary SP, Xie J, Marathe IA, Kostelic M, Greenwald J, Rish AD, Wysocki VH, Chen C, Chen Q, Fu TM, Yu Y.
Nat Struct Mol Biol. 2024 Jan 4.
PMID: 38177683
NUA positively regulates plant immunity by coordination with ESD4 to deSUMOylate TPR1 in Arabidopsis.
Xie B, Luo M, Li Q, Shao J, Chen D, Somers DE, Tang D, Shi H.
New Phytol. 2024 Jan;241(1):363-377.
PMID: 37786257
A tRNA-specific function for tRNA methyltransferase Trm10 is associated with a new tRNA quality control mechanism in Saccharomyces cerevisiae.
Bowles IE, Jackman JE.
RNA. 2024 Jan 16;30(2):171-187.
PMID: 38071471
Patients' perceptions on outcomes after mechanical thrombectomy in acute ischemic stroke.
Thanki S, Pressman E, Jade KM, Skanes R, Armouti A, Guerrero WR, Vakharia K, Parthasarathy AB, Fargen K, Mistry EA, Nimjee SM, Hassan AE, Mokin M.
Interv Neuroradiol. 2024 Jan 23:15910199241227262.
PMID: 38258391
February 2024
Characterization of ribosome stalling and no-go mRNA decay stimulated by the Fragile X protein, FMRP.
Scarpitti MR, Pastore B, Tang W, Kearse MG.
BioRxiv [Preprint]. 2024 Feb 3:2024.02.02.577121.
PMID: 38352534
Immune evasion, infectivity, and fusogenicity of SARS-CoV-2 BA.2.86 and FLip variants.
Qu P, Xu K, Faraone JN, Goodarzi N, Zheng YM, Carlin C, Bednash JS, Horowitz JC, Mallampalli RK, Saif LJ, Oltz EM, Jones D, Gumina RJ, Liu SL.
Cell. 2024 Feb 1;187(3):585-595.e6.
PMID: 38194968
Brief research report: impact of vaccination on antibody responses and mortality from severe COVID-19.
Adhikari B, Bednash JS, Horowitz JC, Rubinstein MP, VlasovaAN.
Front Immunol. 2024 Feb 7;15:1325243.
PMID: 38390335
Pre-piRNA trimming safeguards piRNAs against erroneous targeting by RNA-dependent RNA polymerase.
Pastore B, Hertz HL, Tang W.
Cell Rep. 2024 Feb 27;43(2):113692.
PMID: 38244197
Corrigendum: Brief research report: impact of vaccination on antibody responses and mortality from severe COVID-19.
Adhikari B, Bednash JS, Horowitz JC, Rubinstein MP, VlasovaAN.
Front Immunol. 2024 Feb 28;15:1384209.
PMID: 38482012
Viral potential to modulate microbial methane metabolism varies by habitat.
Zhong ZP, Du J, Köstlbacher S, Pjevac P, Orlić S, Sullivan MB.
NatCommun. 2024 Feb 29;15(1):1857.
PMID: 38424049
Direct Versus Indirect Revascularization for Moyamoya: a Large Multicenter Study.
El Naamani K, Chen CJ, Jabre R, Saad H, Grossberg JA, Dmytriw AA, Patel AB, Khorasanizadeh M, Ogilvy CS, Thomas A, Monteiro A, Siddiqui A, Cortez GM, Hanel RA, Porto G, Spiotta AM, Piscopo AJ, Hasan DM, Ghorbani M, Weinberg J, Nimjee SM, Bekelis K, Salem MM, Burkhardt JK, Zetchi A, Matouk C, Howard BM, Lai R, Du R, Abbas R, Sioutas GS, Amllay A, Munoz A, Atallah E, Herial NA, Tjoumakaris SI, Gooch MR, Rosenwasser RH, Jabbour P.J Neurol Neurosurg Psychiatry. 2024 Feb 14;95(3):256-263.
PMID: 37673641
Stroke and Neurogenesis: Bridging Clinical Observations to New Mechanistic Insights from Animal Models.
Passarelli JP, Nimjee SM, Townsend KL.
Transl Stroke Res. 2024 Feb;15(1):53-68.
PMID: 36462099
An HTLV-1 envelope mRNA vaccine is immunogenic and protective in New Zealand rabbits.
Tu JJ, King E, Maksimova V, Smith S, Macias R, Cheng X, Vegesna T, Yu L, Ratner L, Green PL, Niewiesk S, Richner JM, Panfil AR.
J Virol. 2024 Feb 20;98(2):e0162323.
PMID: 38193692
March 2024
Progress in sarcomas: Highlights from the 2023 annual meetingof the Connective Tissue Oncology Society.
Cripe TP, Roberts RD, Chandler DS, Setty BA, Chen S, Shenoy A, Venkataramany AS, Ringwalt EM, Scharschmidt T, Utset-Ward T, Konieczkowski DJ, Grignol VP, Beane JD, Ruff SM, Pollock RE.
MolTher Oncol. 2024 Mar 2;32(1):200779.
PMID: 38596308
Protein complex heterogeneity and topology revealed by electron capture charge reduction and surface induced dissociation.
Shaw J, Harvey S, Du C, Xu Z, Olmedillas E, Saphire EO, Wysocki VH.
bioRxiv [Preprint]. 2024 Mar 9:2024.03.07.583498.
PMID: 38496594
Distinct Patterns of SARS-CoV-2 BA.2.87.1 and JN.1 Variants in Immune Evasion, Antigenicity and Cell-Cell Fusion.
Li P, Liu Y, Faraone J, Hsu CC, Chamblee M, Zheng YM, Carlin C, Bednash JS, Horowitz JC, Mallampalli RK, Saif LJ, Oltz EM, Jones D, Li J, Gumina RJ, Liu SL.
bioRxiv [Preprint]. 2024 Mar 11:2024.03.11.583978.
PMID: 38559216
Remote Delivery of Mindful Movement Within Healthcare Systems: Lessons Learned From the Veterans Health Administration.
Whitehead AM, Mullur R, Sullivan MB, Nicosia FM.
Glob Adv Integr Med Health. 2024 Mar 17;13:27536130241235908.
PMID: 38501126
Macrophages derived from human induced pluripotent stem cells (iPSCs) serve as a high-fidelity cellular model for investigating HIV-1, dengue, and influenza viruses.
Yang Q, Barbachano-Guerrero A, Fairchild LM, Rowland TJ, Dowell RD, Allen MA, Warren CJ, Sawyer SL.
JVirol. 2024 Mar 19;98(3):e0156323.
PMID: 38323811
The ClC-1 chloride channel inhibitor NMD670 improves skeletal muscle function in rat models and patients with myasthenia gravis.
Skov M, Ruijs TQ, Grønnebæk TS, Skals M, Riisager A, Winther JB, Dybdahl KLT, Findsen A, Morgen JJ, Huus N, Broch-Lips M, Nielsen OB, de Cuba CMKE, Heuberger JAAC, de Kam ML, Tannemaat M, Verschuuren JJGM, Knutsen LJS, Kelly NM, Jensen KG, Arnold WD, Burghes AH, Olesen C, Bold J, Petersen TK, Quiroz JA, Hutchison J, Chin ER, Groeneveld GJ, Pedersen TH.
SciTransl Med. 2024 Mar 20;16(739):eadk9109.
PMID: 38507469 - Clinical Trial
Adaptation of CD4 in gorillas and chimpanzees conveyed resistance to simian immunodeficiency viruses.
Warren CJ, Barbachano-Guerrero A, Bauer VL, Stabell AC, Dirasantha O, Yang Q, Sawyer SL.
bioRxiv [Preprint]. 2024 Mar 25:2023.11.13.566830.
PMID: 38014262
Metamorphic proteins and how to find them.
Porter LL, Artsimovitch I, Ramírez-Sarmiento CA.
CurrOpin Struct Biol. 2024 Mar 26;86:102807.
PMID: 38537533
Cell-cell communication and initial population composition shape the structure of potato spindle tuber viroid quasispecies.
Wu J, Bisaro DM.
Plant Cell. 2024 Mar 29;36(4):1036-1055.
PMID: 38252648
Environment-specific virocell metabolic reprogramming.
Howard-Varona C, Lindback MM, Fudyma JD, Krongauz A, Solonenko NE, Zayed AA, Andreopoulos WB, Olson HM, Kim YM, Kyle JE, Del Rio TG, Adkins JN, Tfaily MM, Paul S, Sullivan MB, Duhaime MB.
ISME J. 2024 Mar 29:wrae055.
PMID: 38552150
Preoperative prescription opioid use as an independent predictor of 90-day mortality and adverse events in craniotomy and craniectomy patients.
Shah VS, Dornbos D, Hoang NA, Cua S, Rodgers B, Pezzutti D, Duenas H, Eaton R, Kreatsoulas D, Elder JB, Prevedello DM, Lonser RR, Nimjee SM.
J Neurosurg. 2024 Mar 8;141(2):455-460.
PMID: 38457788
April 2024
Contribution of an alternative 16S rRNA helix to biogenesis of the 30S subunit of the ribosome.
Warner BR, Fredrick K.
RNA. 2024 Apr 3:rna.079960.124.
PMID: 38570183
RNA three-dimensional structure drives the sequence organization of potato spindle tuber viroid quasispecies.
Wu J, Zhang Y, Nie Y, Yan F, Zirbel CL, Bisaro DM.
PLoSPathog. 2024 Apr 4;20(4):e1012142.
PMID: 38574111
Protein analysis using capillary electrophoresis coupled to mass spectrometry through vibrating sharp-edge spray ionization.
Witzel MT, Veltri LM, Kostelic M, Elshamy YS, Lucas JA, Lai S, Du C, Wysocki VH, Holland LA.
Electrophoresis. 2024 Apr 5.
PMID: 38577828
Concerted transformation of a hyper-paused transcription complex and its reinforcing protein.
Zuber PK, Said N, Hilal T, Wang B, Loll B, González-Higueras J, Ramírez-Sarmiento CA, Belogurov GA, Artsimovitch I, Wahl MC, Knauer SH.
NatCommun. 2024 Apr 8;15(1):3040.
PMID: 38589445
Distinct patterns of SARS-CoV-2 BA.2.87.1 and JN.1 variants in immune evasion, antigenicity, and cell-cell fusion.
Li P, Liu Y, Faraone JN, Hsu CC, Chamblee M, Zheng Y-M, Carlin C, Bednash JS, Horowitz JC, Mallampalli RK, Saif LJ, Oltz EM, Jones D, Li J, Gumina RJ, Liu S-L.
mBio. 2024 May 8;15(5):e0075124.
PMID: 3859189
Single-molecule epitranscriptomic analysis of full-length HIV-1 RNAs reveals functional roles of site-specific m6As.
Baek A, Lee GE, Golconda S, Rayhan A, Manganaris AA, Chen S, Tirumuru N, Yu H, Kim S, Kimmel C, Zablocki O, Sullivan MB, Addepalli B, Wu L, Kim S.
NatMicrobiol. 2024 May;9(5):1340-1355.
PMID: 38605174
Reciprocating RNA Polymerase batters through roadblocks.
Qian J, Cartee A, Xu W, Yan Y, Wang B, Artsimovitch I, Dunlap D, Finzi L.
NatCommun. 2024 Apr 12;15(1):3193.
PMID: 38609371
Sm-like protein Rof inhibits transcription termination factor ρ by binding site obstruction and conformational insulation.
Said N, Finazzo M, Hilal T, Wang B, Selinger TL, Gjorgjevikj D, Artsimovitch I, Wahl MC.
NatCommun. 2024 Apr 15;15(1):3186.
PMID: 38622114
To initiate or not to initiate: A critical assessment of eIF2A, eIF2D, and MCT-1·DENR to deliver initiator tRNA to ribosomes.
Grove DJ, Russell PJ, Kearse MG.
WileyInterdiscip Rev RNA. 2024 Mar-Apr;15(2):e1833.
PMID: 38433101
Molecular basis of Gabija anti-phage supramolecular assemblies.
Yang XY, Shen Z, Xie J, Greenwald J, Marathe I, Lin Q, Xie WJ, Wysocki VH, Fu TM.
Nat Struct Mol Biol. 2024 Apr 16.
PMID: 38627580
Structural Basis for the Interaction of Redβ Single-Strand Annealing Protein with Escherichia coli Single-Stranded DNA-Binding Protein.
Zakharova K, Liu M, Greenwald JR, Caldwell BC, Qi Z, Wysocki VH, Bell CE.
J Mol Biol. 2024 Apr 24;436(11):168590.
PMID: 38663547
Native proteomics by capillary zone electrophoresis-mass spectrometry.
Wang Q, Wang Q, Qi Z, Moeller W, Wysocki VH, Sun L.
bioRxiv [Preprint]. 2024 Apr 28:2024.04.24.590970.
PMID: 38712154
Human T-cell leukemia virus type 1 uses a specific tRNAPro isodecoder to prime reverse transcription.
Syu YC, Hatterschide J, Budding CR, Tang Y, Musier-Forsyth K.
RNA. 2024 Apr 29:rna.080006.124.
PMID: 38684316
Isolation of Diverse Simian Arteriviruses Causing Hemorrhagic Disease.
Shaw TM, Dettle ST, Mejia A, Hayes JM, Simmons HA, Basu P, Kuhn JH, Ramuta MD, Warren CJ, Jahrling PB, O'Connor DH, Huang L, Zaeem M, Seo J, Slukvin II, Brown ME, Bailey AL.
Emerg Infect Dis. 2024 Apr;30(4):721-731.
PMID: 38526136
Stroke Thrombolysis: Can You Feel the Need for Speed?
Nimjee SM, Hill MD.
Neurology. 2024 Apr 9;102(7):e209253.
PMID: 38502898
May 2024
Structural basis of nearest-neighbor cooperativity in the ring-shaped gene regulatory protein TRAP from protein engineering and cryo-EM.
Li W, Yang H, Stachowski K, Norris AS, Lichtenthal K, Kelly S, Gollnick P, Wysocki VH, Foster MP.
bioRxiv [Preprint]. 2024 May 5:2024.05.02.592192.
PMID: 38746386
A tribute to Sidney Altman, one of the architects of modern RNA biology.
Gopalan V, Kirsebom LA.
J Biol Chem. 2024 May 10:107364.
PMID: 38735479
Long-read powered viral metagenomics in the oligotrophic Sargasso Sea.
Warwick-Dugdale J, Tian F, Michelsen ML, Cronin DR, Moore K, Farbos A, Chittick L, Bell A, Zayed AA, Buchholz HH, Bolanos LM, Parsons RJ, Allen MJ, Sullivan MB, Temperton B.
NatCommun. 2024 May 14;15(1):4089.
PMID: 38744831
Overexpression of stress granule protein TZF1 enhances salt stress tolerance by targeting ACA11 mRNA for degradation in Arabidopsis.
He SL, Li B, Zahurancik WJ, Arthur HC, Sidharthan V, Gopalan V, Wang L, Jang JC.
Front Plant Sci. 2024 May 8;15:1375478.
PMID: 38799098
Paramutation at the maize pl1 locus is associated with RdDM activity at distal tandem repeats.
Deans NC, Talbot JRB, Li M, Sáez-González C, Hövel I, Heavens D, Stam M, Hollick JB.
PLoS Genet. 2024 May 30;20(5):e1011296.
PMID: 38814980
Thg1 family 3'-5' RNA polymerases as tools for targeted RNA synthesis.\
Jayasinghe MI, Patel KJ, Jackman JE.
RNA. 2024 Sep 16;30(10):1315-1327.
PMID: 3899712
Characteristics of JN.1-derived SARS-CoV-2 subvariants SLip, FLiRT, and KP.2 in neutralization escape, infectivity and membrane fusion.
Li P, Faraone JN, Hsu CC, Chamblee M, Zheng YM, Carlin C, Bednash JS, Horowitz JC, Mallampalli RK, Saif LJ, Oltz EM, Jones D, Li J, Gumina RJ, Xu K, Liu SL.
bioRxiv [Preprint]. 2024 May 21:2024.05.20.595020.
PMID: 38826376
June 2024
Solution structure, dynamics and tetrahedral assembly of Anti-TRAP, a homo-trimeric triskelion-shaped regulator of tryptophan biosynthesis in Bacillus subtilis.
McElroy CA, Ihms EC, Kumar Yadav D, Holmquist ML, Wadhwa V, Wysocki VH, Gollnick P, Foster MP.
J Struct Biol X. 2024 Jun 11;10:100103.
PMID: 39035014
Contribution of an alternative 16S rRNA helix to biogenesis of the 30S subunit of the ribosome.
Warner BR, Fredrick K.
RNA. 2024 Jun 17;30(7):770-778.
PMID: 38570183
KDM2B is required for ribosome biogenesis and its depletion unequally affects mRNA translation.
Anastas V, Chavdoula E, La Ferlita A, Soysal B, Cosentini I, Nigita G, Kearse MG, Tsichlis PN.
bioRxiv [Preprint]. 2024 Jun 6:2024.05.22.595403.
PMID: 38826406
Nucleolin acute degradation reveals novel functions in cell cycle progression and division in TNBC.
Mills J, Tessari A, Anastas V, Kumar DS, Rad NS, Lamba S, Cosentini I, Reers A, Zhu Z, Miles WO, Coppola V, Cocucci E, Magliery TJ, Shive H, Davies AE, Rizzotto L, Croce CM, Palmieri D.
bioRxiv [Preprint]. 2024 Jun 22:2024.06.17.599429.
PMID: 38948867
Microbial polyphenol metabolism is part of the thawing permafrost carbon cycle.
McGivern BB, Cronin DR, Ellenbogen JB, Borton MA, Knutson EL, Freire-Zapata V, Bouranis JA, Bernhardt L, Hernandez AI, Flynn RM, Woyda R, Cory AB, Wilson RM, Chanton JP, Woodcroft BJ, Ernakovich JG, Tfaily MM, Sullivan MB, Tyson GW, Rich VI, Hagerman AE, Wrighton KC.
Nat Microbiol. 2024 Jun;9(6):1454-1466.
PMID: 38806673
2023 Publications