Publications

January 2025

Design of a yeast SUMO tag to eliminate internal translation initiation.
Law JD, Gao Y, Wysocki VH, Gopalan V.
Protein Sci. 2025 Jan;34(1):e5256.  
PMID: 39692120   

Riluzole Enhancing Anti-PD-1 Efficacy by Activating cGAS/STING Signaling in Colorectal Cancer.
Liang B, Khan M, Storts H, Zhang EH, Zheng X, Xing X, Claybon H, Wilson J, Li C, Jin N, Fishel R, Miles WO, Wang J
J.Mol Cancer Ther. 2025 Jan 2;24(1):131-140. 
PMID: 39382075

Regulation of sod1 mRNA and protein abundance by zinc in fission yeast is dependent on the CCR4-NOT complex.
Weeks AT, Bird AJ.
J Biol Chem. 2025 Jan 4:108156. 
PMID: 39761853 

The Psu protein of phage satellite P4 inhibits transcription termination factor ρ by forced hyper-oligomerization.
Gjorgjevikj D, Kumar N, Wang B, Hilal T, Said N, Loll B, Artsimovitch I, Sen R, Wahl MC
Nat Commun
PMID: 39788982

Structural basis of nearest-neighbor cooperativity in the ring-shaped gene regulatory protein TRAP from protein engineering and cryo-EM
Li W, Yang H, Stachowski K, Norris AS, Lichtenthal K, Kelly S, Gollnick P, Wysocki VH, Foster MP
Proc Natl Acad Sci USA.
PMID: 3979304

Role of the sarcin-ricin loop of 23S rRNA in biogenesis of the 50S ribosomal subunit.
Fakhretaha Aval S, Seffouh A, Moon KM, Foster L, Ortega J, Fredrick K
RNA. 
PMID: 39875174.

Complexes of vertebrate TMC1/2 and CIB2/3 proteins form hair-cell mechanotransduction cation channels.
Giese APJ, Weng WH, Kindt KS, Chang HHV, Montgomery JS, Ratzan EM, Beirl AJ, Aponte Rivera R, Lotthammer JM, Walujkar S, Foster MP, Zobeiri OA, Holt JR, Riazuddin S, Cullen KE, Sotomayor M, Ahmed ZM. 
Elife.
PMID: 39773557.

Use of a small molecule microarray screen to identify inhibitors of the catalytic RNA subunit of Methanobrevibacter smithii RNase P.
Sidharthan V, Sibley CD, Dunne-Dombrink K, Yang M, Zahurancik WJ, Balaratnam S, Wilburn DB, Schneekloth JS Jr, Gopalan V
Nucleic Acids Res.
PMID: 39676671.

Histamine N-methyltransferase (HNMT) as a potential auxiliary biomarker for predicting adaptability to anti-HER2 drug treatment in breast cancer patients.
Cheng TC, Hung MC, Wang LH, Tu SH, Wu CH, Yen Y, Chen CL, Whang-Peng J, Lee WJ, Liao YC, Lee YC, Pan MH, Lin HK, Tzeng HE, Guo P, Chu CY, Chen LC, Ho YS
Biomark Res.
PMID: 39789599

Inhibition of Endothelial Cell Tube Formation by Anti-Vascular Endothelial Growth Factor/Anti-Angiopoietin-2 RNA Nanoparticles.
Zhong C, Shi Z, Liu CY, Binzel DW, Jin K, Li X, Guo P, Li SK.  
Pharmaceutics
PMID: 39861703
 
February 2025  

ncRNA Editing: Functional Characterization and Computational Resources.
Marceca GP, Romano G, Acunzo M, Nigita G.
Methods Mol Biol
PMID: 39702721

Free introns of tRNAs as complementarity-dependent regulators of gene expression. 
Nostramo RT, Sinopoli PL, Bao A, Metcalf S, Peltier LM, Hopper AK
Mol Cell. 
PMID: 39938518

Nucleotide-induced hyper-oligomerization inactivates transcription termination factor ρ
Wang B, Said N, Hilal T, Finazzo M, Wahl MC, Artsimovitch I.
Nat Commun
PMID: 39952913

Identification of inhibitors of the Salmonella FraB deglycase, a drug target.
Law JD, Gao Y, Kovvali S, Thirugnanasambantham P, Wysocki VH, Ahmer BMM, Gopalan V
FEBS Open Bio.
PMID: 39945759.

Protein bL38 facilitates incorporation of uL6 during assembly of the 50S subunit in Flavobacterium johnsoniae
Alom MS, Arpin D, Zhu H, Hay BN, Foster LJ, Ortega J, Fredrick K
Nucleic Acids Res
PMID: 39997215

Conformational dynamics in specialized C2H2zinc finger domains enable zinc-responsive gene repression in S. pombe.
Wadhwa V, Jamshidi C, Stachowski K, Bird AJ, Foster MP
Protein Sci
PMID: 39865413

Cardiac transcriptional enhancer is repurposed during regeneration to activate an anti-proliferative program.
Rao A, Russell A, Segura-Bermudez J, Franz C, Dockery R, Blatnik A, Panten J, Zevallos M, McNulty C, Pietrzak M, Goldman JA
Development
PMID: 39803985

Sustained release of RNA nanoparticles from reservoir implant for ocular delivery.
Shi Z, Zhong C, Binzel DW, Jin K, Guo P, Li SK. 
J Pharm Sci
PMID: 39725224

Structural basis for aminoacylation of cellular modified tRNALys3 by human lysyl-tRNA synthetase.
Devarkar SC, Budding CR, Pathirage C, Kavoor A, Herbert C, Limbach PA, Musier-Forsyth K, Xiong Y. 
Nucleic Acids Res
PMID: 40036503

An AT-hook transcription factor promotes transcription of histone, spliced-leader, and piRNA clusters.
Wang YH, Hertz HL, Pastore B, Tang W
Nucleic Acids Res
PMID: 39945323

March 2025

Protein and DNA Conformational Changes Contribute to Specificity of Cre Recombinase.
Montgomery JS, Judson ME, Foster MP.
Biochemistry
PMID: 39957070.

2024 Publications

2023 Publications