Federica Accornero
Underlying heart and skeletal muscle diseases, with a primary focus on the role of RNA-binding proteins in regulating the expression of pathologic genes during stress challenges.
Juan Alfonzo
Editing and Modification of tRNA: Roles in Mitochondrial Biogenesis and Disease
Sharon Amacher
RNA processing during vertebrate development; RNA decay; muscle-specific RNA splicing
Irina Artsimovitch
Molecular mechanism and regulation of transcription
Amanda Bird
Roles of metal ions in RNA metabolism; ncRNAs
David Bisaro
Viral pathogenesis, small RNA-directed chromatin methylation, viral suppression of transcriptional and post-transcriptional gene silencing
Dennis Bong
RNA-DNA complexation and functional modulation by synthetic bifacial peptide nucleic acid
Ralf Bundschuh
Computational modeling of RNA structure and kinetics, RNA editing, sequence analysis
Moray Campbell
Epigenomic mechanisms that re-wire nuclear hormone receptor signalling in cancer
Dawn Chandler
Mechanisms of alternative pre-mRNA splicing in the DNA damage response
Susan Cole
We are broadly interested in how cells communicate during embryonic development, how post-transcriptional regulation controls this communication, and how changes in cell signaling pathways influence congenital defects and diseases such as cancer.
Mark Foster
Protein-nucleic acid interactions, NMR spectroscopy, biophysical methods
Venkat Gopalan
Structure-function relationships in RNase P, a catalytic RNP complex
Peixuan Guo
RNA Nanbiotechnology for siRNA/drug delivery; structure, function and applications of the RNA-geared phi29 DNA packaging nanomotor; single molecule imaging using Total Internal Reflection Fluorescence (TIRF) Microscopy and Optical Tweezers; single pore sensing using the connector of phi29 DNA packaging.
Tina M Henkin
How nascent transcripts recognize specific effectors and use that information to control gene expression
Paul K Herman
Regulation of eukaryotic cell proliferation; Functions of ribonucleoprotein complexes in quiescent cells
Jay B Hollick
Epigenetic mechanisms of gene control, Chromosome structure and function
Anita Hopper
Intracellular trafficking of RNA and proteins; Nucleus organization; RNA processing
Jane Jackman
Molecular mechanisms of tRNA processing enzymes
JC Jang
• Sugar sensing and signaling in higher plants • Plant hormone signal transduction • Post-transcriptional regulation of gene expression
Michael Kearse
Defining novel mechanisms of how mRNA translation is regulated and affected in human biology and disease.
Stephen J Kolb
RNA metabolism in neurological diseases
Shan-Lu Liu
Role of IFN-stimulated genes in HIV, Ebolavirus and Zika virus infection, RNA virus assembly and release, viral oncogenesis and human lung cancer
Iris Meier
Anchoring of Ran signal transduction in plants, Nuclear pore and nuclear envelope protein function, and Genomic a nalysis of long coiled-coil proteins
Wayne Miles
Studying the roles of RNA-binding proteins in controlling the oncogenic growth of cells lacking the Retinoblastoma 1 tumor-suppressor gene.
Karin Musier-Forsyth
Aminoacyl-tRNA synthetases and nucleic acid-protein interactions in HIV
Kotaro Nakanishi
Our research interest focuses on elucidating the mechanism of microRNA (miRNA)-mediated gene regulations underlying cell type determination
Shahid M. Nimjee
My research focuses on the discovery and development of therapeutic RNAs to treat pathological thrombosis in treating diseases like stroke, carotid, cardiovascular and peripheral vascular disease.
Guramrit Singh
Control of post-transcriptional gene expression by dynamic ribonucleoprotein (RNP) complexes
Matthew Sullivan
Phage ecology, evolution and discovery; Phage-host interaction biology via genome-wide ‘omics analyses
Wen Tang
Research interest: Small RNA biology and mechanisms of epigenetic inheritance
Li-Chun Tu
Chromatin organization and dynamics; epigenetic regulation in normal and cancer cells
Robin Wharton
Translational control during Drosophila development
Vicki Wysocki
Mass Spectrometry Based Structural Biology, Bioanalytical Mass Spectrometry.