Center for RNA Biology Publications

Publications by Irina Artsimovitch since 2000

• Nataliya Miropolskaya, Irina Artsimovitch, Saulius Klimasauskas, Vadim Nikiforov, and Andrey Kulbachinskiy
  "Allosteric control of catalysis by the F loop of RNA polymerase."
  Proc. Natl. Acad. Sci. U.S.A. 106, 18942-7 (2009).

• Georgiy A Belogurov, Rachel A Mooney, Vladimir Svetlov, Robert Landick, and Irina Artsimovitch
  "Functional specialization of transcription elongation factors."
  EMBO J. 28, 112-22 (2009).

• Georgiy A Belogurov, Marina N Vassylyeva, Anastasiya Sevostyanova, James R Appleman, Alan X Xiang, Ricardo Lira, Stephen E Webber, Sergiy Klyuyev, Evgeny Nudler, Irina Artsimovitch, and Dmitry G Vassylyev
  "Transcription inactivation through local refolding of the RNA polymerase structure."
  Nature 457, 332-5 (2009).

• Irina Artsimovitch and Tina M Henkin
  "In vitro approaches to analysis of transcription termination."
  Methods 47, 37-43 (2009).

• Irina Artsimovitch
  "Post-initiation control by the initiation factor sigma."
  Mol. Microbiol. 68, 1-3 (2008).

• Anastasiya Sevostyanova, Vladimir Svetlov, Dmitry G Vassylyev, and Irina Artsimovitch
  "The elongation factor RfaH and the initiation factor sigma bind to the same site on the transcription elongation complex."
  Proc. Natl. Acad. Sci. U.S.A. 105, 865-70 (2008).

• Irina Artsimovitch and Dmitry G Vassylyev
  "Merging the RNA and DNA worlds."
  Nat. Struct. Mol. Biol. 14, 1122-3 (2007).

• Marina N Vassylyeva, Vladimir Svetlov, Altaira D Dearborn, Sergiy Klyuyev, Irina Artsimovitch, and Dmitry G Vassylyev
  "The carboxy-terminal coiled-coil of the RNA polymerase beta-subunit is the main binding site for Gre factors."
  EMBO Rep. 8, 1038-43 (2007).

• Dmitry G Vassylyev, Marina N Vassylyeva, Jinwei Zhang, Murali Palangat, Irina Artsimovitch, and Robert Landick
  "Structural basis for substrate loading in bacterial RNA polymerase."
  Nature 448, 163-8 (2007).

• Dmitry G Vassylyev, Marina N Vassylyeva, Anna Perederina, Tahir H Tahirov, and Irina Artsimovitch
  "Structural basis for transcription elongation by bacterial RNA polymerase."
  Nature 448, 157-62 (2007).

• Georgiy A Belogurov, Marina N Vassylyeva, Vladimir Svetlov, Sergiy Klyuyev, Nick V Grishin, Dmitry G Vassylyev, and Irina Artsimovitch
  "Structural basis for converting a general transcription factor into an operon-specific virulence regulator."
  Mol. Cell 26, 117-29 (2007).

• Vladimir Svetlov, Georgiy A Belogurov, Elena Shabrova, Dmitry G Vassylyev, and Irina Artsimovitch
  "Allosteric control of the RNA polymerase by the elongation factor RfaH."
  Nucleic Acids Res. 35, 5694-705 (2007).

• Marina N Vassylyeva, Vladimir Svetlov, Sergiy Klyuyev, Yancho D Devedjiev, Irina Artsimovitch, and Dmitry G Vassylyev
  "Crystallization and preliminary crystallographic analysis of the transcriptional regulator RfaH from Escherichia coli and its complex with ops DNA."
  Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 62, 1027-30 (2006).

• Irina Artsimovitch and Dmitry G Vassylyev
  "Is it easy to stop RNA polymerase"
  Cell Cycle 5, 399-404 (2006).

• Jindrich Symersky, Anna Perederina, Marina N Vassylyeva, Vladimir Svetlov, Irina Artsimovitch, and Dmitry G Vassylyev
  "Regulation through the RNA polymerase secondary channel. Structural and functional variability of the coiled-coil transcription factors."
  J. Biol. Chem. 281, 1309-12 (2006).

• Anna A Perederina, Marina N Vassylyeva, Igor A Berezin, Vladimir Svetlov, Irina Artsimovitch, and Dmitry G Vassylyev
  "Cloning, expression, purification, crystallization and initial crystallographic analysis of transcription elongation factors GreB from Escherichia coli and Gfh1 from Thermus thermophilus."
  Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 62, 44-6 (2006).

• Dmitry G Vassylyev and Irina Artsimovitch
  "Tracking RNA polymerase, one step at a time."
  Cell 123, 977-9 (2005).

• Dmitry G Vassylyev, Vladimir Svetlov, Marina N Vassylyeva, Anna Perederina, Noriyuki Igarashi, Naohiro Matsugaki, Soichi Wakatsuki, and Irina Artsimovitch
  "Structural basis for transcription inhibition by tagetitoxin."
  Nat. Struct. Mol. Biol. 12, 1086-93 (2005).

• Irina Artsimovitch, Marina N Vassylyeva, Dmitri Svetlov, Vladimir Svetlov, Anna Perederina, Noriyuki Igarashi, Naohiro Matsugaki, Soichi Wakatsuki, Tahir H Tahirov, and Dmitry G Vassylyev
  "Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins."
  Cell 122, 351-63 (2005).

• Francine Toulmé, Christine Mosrin-Huaman, Irina Artsimovitch, and A Rachid Rahmouni
  "Transcriptional pausing in vivo a nascent RNA hairpin restricts lateral movements of RNA polymerase in both forward and reverse directions."
  J. Mol. Biol. 351, 39-51 (2005).

• D Vicari and I Artsimovitch
  "Virulence regulators RfaH and YaeQ do not operate in the same pathway."
  Mol. Genet. Genomics 272, 489-96 (2004).

• Vladimir Svetlov, Dmitry G Vassylyev, and Irina Artsimovitch
  "Discrimination against deoxyribonucleotide substrates by bacterial RNA polymerase."
  J. Biol. Chem. 279, 38087-90 (2004).

• Marina N Vassylyeva, Anna A Perederina, Vladimir Svetlov, Shigeyuki Yokoyama, Irina Artsimovitch, and Dmitry G Vassylyev
  "Cloning, expression, purification, crystallization and initial crystallographic analysis of transcription factor DksA from Escherichia coli."
  Acta Crystallogr. D Biol. Crystallogr. 60, 1611-3 (2004).

• Anna Perederina, Vladimir Svetlov, Marina N Vassylyeva, Tahir H Tahirov, Shigeyuki Yokoyama, Irina Artsimovitch, and Dmitry G Vassylyev
  "Regulation through the secondary channel--structural framework for ppGpp-DksA synergism during transcription."
  Cell 118, 297-309 (2004).

• Heather D Carter, Vladimir Svetlov, and Irina Artsimovitch
  "Highly divergent RfaH orthologs from pathogenic proteobacteria can substitute for Escherichia coli RfaH both in vivo and in vitro."
  J. Bacteriol. 186, 2829-40 (2004).

• Irina Artsimovitch, Vsevolod Patlan, Shun-ichi Sekine, Marina N Vassylyeva, Takeshi Hosaka, Kozo Ochi, Shigeyuki Yokoyama, and Dmitry G Vassylyev
  "Structural basis for transcription regulation by alarmone ppGpp."
  Cell 117, 299-310 (2004).

• Irina Artsimovitch, Clement Chu, A Simon Lynch, and Robert Landick
  "A new class of bacterial RNA polymerase inhibitor affects nucleotide addition."
  Science 302, 650-4 (2003).

• Irina Artsimovitch, Vladimir Svetlov, Katsuhiko S Murakami, and Robert Landick
  "Co-overexpression of Escherichia coli RNA polymerase subunits allows isolation and analysis of mutant enzymes lacking lineage-specific sequence insertions."
  J. Biol. Chem. 278, 12344-55 (2003).

• Brooke A Murphy McDaniel, Frank J Grundy, Irina Artsimovitch, and Tina M Henkin
  "Transcription termination control of the S box system direct measurement of S-adenosylmethionine by the leader RNA."
  Proc. Natl. Acad. Sci. U.S.A. 100, 3083-8 (2003).

• Julia Yuzenkova, Monica Delgado, Sergei Nechaev, Dhruti Savalia, Vitaly Epshtein, Irina Artsimovitch, Rachel A Mooney, Robert Landick, Ricardo N Farias, Raul Salomon, and Konstantin Severinov
  "Mutations of bacterial RNA polymerase leading to resistance to microcin j25."
  J. Biol. Chem. 277, 50867-75 (2002).

• Josefine Ederth, Irina Artsimovitch, Leif A Isaksson, and Robert Landick
  "The downstream DNA jaw of bacterial RNA polymerase facilitates both transcriptional initiation and pausing."
  J. Biol. Chem. 277, 37456-63 (2002).

• Irina Artsimovitch and Robert Landick
  "The transcriptional regulator RfaH stimulates RNA chain synthesis after recruitment to elongation complexes by the exposed nontemplate DNA strand."
  Cell 109, 193-203 (2002).

• T M Gruber, D Markov, M M Sharp, B A Young, C Z Lu, H J Zhong, I Artsimovitch, K M Geszvain, T M Arthur, R R Burgess, R Landick, K Severinov, and C A Gross
  "Binding of the initiation factor sigma70 to core RNA polymerase is a multistep process."
  Mol. Cell 8, 21-31 (2001).

• I Toulokhonov, I Artsimovitch, and R Landick
  "Allosteric control of RNA polymerase by a site that contacts nascent RNA hairpins."
  Science 292, 730-3 (2001).

• I Artsimovitch, V Svetlov, L Anthony, R R Burgess, and R Landick
  "RNA polymerases from Bacillus subtilis and Escherichia coli differ in recognition of regulatory signals in vitro."
  J. Bacteriol. 182, 6027-35 (2000).

• L C Anthony, I Artsimovitch, V Svetlov, R Landick, and R R Burgess
  "Rapid purification of His6-tagged Bacillus subtilis core RNA polymerase."
  Protein Expr. Purif. 19, 350-4 (2000).

• I Artsimovitch and R Landick
  "Pausing by bacterial RNA polymerase is mediated by mechanistically distinct classes of signals."
  Proc. Natl. Acad. Sci. U.S.A. 97, 7090-5 (2000).