Center for RNA Biology Publications

Publications by Karin Musier-Forsyth since 2000

• Anjali P Mascarenhas and Karin Musier-Forsyth
  "The capsid protein of human immunodeficiency virus: interactions of HIV-1 capsid with host protein factors."
  FEBS J. 276, 6118-27 (2009).

• Klara Post, Besik Kankia, Swathi Gopalakrishnan, Victoria Yang, Elizabeth Cramer, Pilar Saladores, Robert J Gorelick, Jianhui Guo, Karin Musier-Forsyth, and Judith G Levin
  "Fidelity of plus-strand priming requires the nucleic acid chaperone activity of HIV-1 nucleocapsid protein."
  Nucleic Acids Res. 37, 1755-66 (2009).

• Jiqiang Ling, Byung Ran So, Srujana S Yadavalli, Hervé Roy, Shinichiro Shoji, Kurt Fredrick, Karin Musier-Forsyth, and Michael Ibba
  "Resampling and editing of mischarged tRNA prior to translation elongation."
  Mol. Cell 33, 654-60 (2009).

• Yan Chen, Bin Wu, Karin Musier-Forsyth, Louis M Mansky, and Joachim D Mueller
  "Fluorescence fluctuation spectroscopy on viral-like particles reveals variable gag stoichiometry."
  Biophys. J. 96, 1961-9 (2009).

• My-Nuong Vo, George Barany, Ioulia Rouzina, and Karin Musier-Forsyth
  "HIV-1 nucleocapsid protein switches the pathway of transactivation response element RNA/DNA annealing from loop-loop "
  J. Mol. Biol. 386, 789-801 (2009).

• My-Nuong Vo, George Barany, Ioulia Rouzina, and Karin Musier-Forsyth
  "Effect of Mg2 and Na on the nucleic acid chaperone activity of HIV-1 nucleocapsid protein: implications for reverse transcription."
  J. Mol. Biol. 386, 773-88 (2009).

• Srujana S Yadavalli, Karin Musier-Forsyth, and Michael Ibba
  "The return of pretransfer editing in protein synthesis."
  Proc. Natl. Acad. Sci. U.S.A. 105, 19031-2 (2008).

• Min Wei, Yiliang Yang, Meijuan Niu, Laurie Desfosse, Robert Kennedy, Karin Musier-Forsyth, and Lawrence Kleiman
  "Inability of human immunodeficiency virus type 1 produced in murine cells to selectively incorporate primer formula."
  J. Virol. 82, 12049-59 (2008).

• Kristen M Stewart-Maynard, Margareta Cruceanu, Fei Wang, My-Nuong Vo, Robert J Gorelick, Mark C Williams, Ioulia Rouzina, and Karin Musier-Forsyth
  "Retroviral nucleocapsid proteins display nonequivalent levels of nucleic acid chaperone activity."
  J. Virol. 82, 10129-42 (2008).

• Brian Burke, Songon An, and Karin Musier-Forsyth
  "Functional guanine-arginine interaction between tRNAPro and prolyl-tRNA synthetase that couples binding and catalysis."
  Biochim. Biophys. Acta 1784, 1222-5 (2008).

• Songon An, George Barany, and Karin Musier-Forsyth
  "Evolution of acceptor stem tRNA recognition by class II prolyl-tRNA synthetase."
  Nucleic Acids Res. 36, 2514-21 (2008).

• Kathryn E Splan, Michael E Ignatov, and Karin Musier-Forsyth
  "Transfer RNA modulates the editing mechanism used by class II prolyl-tRNA synthetase."
  J. Biol. Chem. 283, 7128-34 (2008).

• Min Guo, Michael Ignatov, Karin Musier-Forsyth, Paul Schimmel, and Xiang-Lei Yang
  "Crystal structure of tetrameric form of human lysyl-tRNA synthetase Implications for multisynthetase complex formation."
  Proc. Natl. Acad. Sci. U.S.A. 105, 2331-6 (2008).

• Kathryn E Splan, Karin Musier-Forsyth, Michal T Boniecki, and Susan A Martinis
  "In vitro assays for the determination of aminoacyl-tRNA synthetase editing activity."
  Methods 44, 119-28 (2008).

• Brandie J Kovaleski, Robert Kennedy, Ahmad Khorchid, Lawrence Kleiman, Hiroshi Matsuo, and Karin Musier-Forsyth
  "Critical role of helix 4 of HIV-1 capsid C-terminal domain in interactions with human lysyl-tRNA synthetase."
  J. Biol. Chem. 282, 32274-9 (2007).

• Christy F Landes, Yining Zeng, Hsiao-Wei Liu, Karin Musier-Forsyth, and Paul F Barbara
  "Single-molecule study of the inhibition of HIV-1 transactivation response region DNA/DNA annealing by argininamide."
  J. Am. Chem. Soc. 129, 10181-8 (2007).

• Yining Zeng, Hsiao-Wei Liu, Christy F Landes, Yoen Joo Kim, Xiaojing Ma, Yongjin Zhu, Karin Musier-Forsyth, and Paul F Barbara
  "Probing nucleation, reverse annealing, and chaperone function along the reaction path of HIV-1 single-strand transfer."
  Proc. Natl. Acad. Sci. U.S.A. 104, 12651-6 (2007).

• Besik I Kankia and Karin Musier-Forsyth
  "The HIV-1 central DNA flap region contains a "
  Biophys. Chem. 127, 64-8 (2007).

• Hsiao-Wei Liu, Yining Zeng, Christy F Landes, Yoen Joo Kim, Yongjin Zhu, Xiaojing Ma, My-Nuong Vo, Karin Musier-Forsyth, and Paul F Barbara
  "Insights on the role of nucleic acid/protein interactions in chaperoned nucleic acid rearrangements of HIV-1 reverse transcription."
  Proc. Natl. Acad. Sci. U.S.A. 104, 5261-7 (2007).

• Julius SternJohn, Sanchita Hati, Paul G Siliciano, and Karin Musier-Forsyth
  "Restoring species-specific posttransfer editing activity to a synthetase with a defunct editing domain."
  Proc. Natl. Acad. Sci. U.S.A. 104, 2127-32 (2007).

• Yasumasa Iwatani, Denise S B Chan, F Wang, Kristen Stewart Maynard, Wataru Sugiura, Angela M Gronenborn, Ioulia Rouzina, Mark C Williams, Karin Musier-Forsyth, and Judith G Levin
  "Deaminase-independent inhibition of HIV-1 reverse transcription by APOBEC3G."
  Nucleic Acids Res. 35, 7096-108 (2007).

• Margareta Cruceanu, Robert J Gorelick, Karin Musier-Forsyth, Ioulia Rouzina, and Mark C Williams
  "Rapid kinetics of protein-nucleic acid interaction is a major component of HIV-1 nucleocapsid proteins nucleic acid chaperone function."
  J. Mol. Biol. 363, 867-77 (2006).

• My-Nuong Vo, George Barany, Ioulia Rouzina, and Karin Musier-Forsyth
  "Mechanistic studies of mini-TAR RNA/DNA annealing in the absence and presence of HIV-1 nucleocapsid protein."
  J. Mol. Biol. 363, 244-61 (2006).

• Sanchita Hati, Brigitte Ziervogel, Julius Sternjohn, Fai-Chu Wong, Maria C Nagan, Abbey E Rosen, Paul G Siliciano, Joseph W Chihade, and Karin Musier-Forsyth
  "Pre-transfer editing by class II prolyl-tRNA synthetase role of aminoacylation active site in "
  J. Biol. Chem. 281, 27862-72 (2006).

• Brandie J Kovaleski, Robert Kennedy, Minh K Hong, Siddhartha A Datta, Lawrence Kleiman, Alan Rein, and Karin Musier-Forsyth
  "In vitro characterization of the interaction between HIV-1 Gag and human lysyl-tRNA synthetase."
  J. Biol. Chem. 281, 19449-56 (2006).

• Abbey E Rosen, Bonnie S Brooks, Ethan Guth, Christopher S Francklyn, and Karin Musier-Forsyth
  "Evolutionary conservation of a functionally important backbone phosphate group critical for aminoacylation of histidine tRNAs."
  RNA 12, 1315-22 (2006).

• Gonzalo Cosa, Yining Zeng, Hsiao-Wei Liu, Christy F Landes, Dmitrii E Makarov, Karin Musier-Forsyth, and Paul F Barbara
  "Evidence for non-two-state kinetics in the nucleocapsid protein chaperoned opening of DNA hairpins."
  The journal of physical chemistry. B 110, 2419-26 (2006).

• Yariv Y Pinto, John D Le, Nadrian C Seeman, Karin Musier-Forsyth, T Andrew Taton, and Richard A Kiehl
  "Sequence-encoded self-assembly of multiple-nanocomponent arrays by 2D DNA scaffolding."
  Nano Lett. 5, 2399-402 (2005).

• Hsiao-Wei Liu, Gonzalo Cosa, Christy F Landes, Yining Zeng, Brandie J Kovaleski, Daniel G Mullen, George Barany, Karin Musier-Forsyth, and Paul F Barbara
  "Single-molecule FRET studies of important intermediates in the nucleocapsid-protein-chaperoned minus-strand transfer step in HIV-1 reverse transcription."
  Biophys. J. 89, 3470-9 (2005).

• Songon An and Karin Musier-Forsyth
  "Cys-tRNAPro editing by Haemophilus influenzae YbaK via a novel synthetase.YbaK.tRNA ternary complex."
  J. Biol. Chem. 280, 34465-72 (2005).

• Besik I Kankia, George Barany, and Karin Musier-Forsyth
  "Unfolding of DNA quadruplexes induced by HIV-1 nucleocapsid protein."
  Nucleic Acids Res. 33, 4395-403 (2005).

• Judith G Levin, Jianhui Guo, Ioulia Rouzina, and Karin Musier-Forsyth
  "Nucleic acid chaperone activity of HIV-1 nucleocapsid protein critical role in reverse transcription and molecular mechanism."
  Prog. Nucleic Acid Res. Mol. Biol. 80, 217-86 (2005).

• Songon An and Karin Musier-Forsyth
  "Trans-editing of Cys-tRNAPro by Haemophilus influenzae YbaK protein."
  J. Biol. Chem. 279, 42359-62 (2004).

• Gonzalo Cosa, Elizabeth J Harbron, Yining Zeng, Hsiao-Wei Liu, Donald B OConnor, Chie Eta-Hosokawa, Karin Musier-Forsyth, and Paul F Barbara
  "Secondary structure and secondary structure dynamics of DNA hairpins complexed with HIV-1 NC protein."
  Biophys. J. 87, 2759-67 (2004).

• Nilhan Gunasekera, Sang Won Lee, Sunghoon Kim, Karin Musier-Forsyth, and Edgar Arriaga
  "Nuclear localization of aminoacyl-tRNA synthetases using single-cell capillary electrophoresis laser-induced fluorescence analysis."
  Anal. Chem. 76, 4741-6 (2004).

• Nilhan Gunasekera, Guohua Xiong, Karin Musier-Forsyth, and Edgar Arriaga
  "A capillary electrophoretic method for monitoring the presence of alpha-tubulin in nuclear preparations."
  Anal. Biochem. 330, 1-9 (2004).

• Michele R S Hargittai, Robert J Gorelick, Ioulia Rouzina, and Karin Musier-Forsyth
  "Mechanistic insights into the kinetics of HIV-1 nucleocapsid protein-facilitated tRNA annealing to the primer binding site."
  J. Mol. Biol. 337, 951-68 (2004).

• Susan A Connolly, Abbey E Rosen, Karin Musier-Forsyth, and Christopher S Francklyn
  "G-1C73 recognition by an arginine cluster in the active site of Escherichia coli histidyl-tRNA synthetase."
  Biochemistry 43, 962-9 (2004).

• Nilhan Gunasekera, Karen J Olson, Karin Musier-Forsyth, and Edgar A Arriaga
  "Capillary electrophoretic separation of nuclei released from single cells."
  Anal. Chem. 76, 655-62 (2004).

• Abbey E Rosen and Karin Musier-Forsyth
  "Recognition of G-1C73 atomic groups by Escherichia coli histidyl-tRNA synthetase."
  J. Am. Chem. Soc. 126, 64-5 (2004).

• Fai-Chu Wong, Penny J Beuning, Carmen Silvers, and Karin Musier-Forsyth
  "An isolated class II aminoacyl-tRNA synthetase insertion domain is functional in amino acid editing."
  J. Biol. Chem. 278, 52857-64 (2003).

• Mahadevan Seetharaman, Caroline Williams, Christopher J Cramer, and Karin Musier-Forsyth
  "Effect of G-1 on histidine tRNA microhelix conformation."
  Nucleic Acids Res. 31, 7311-21 (2003).

• Nick Lee, Robert J Gorelick, and Karin Musier-Forsyth
  "Zinc finger-dependent HIV-1 nucleocapsid protein-TAR RNA interactions."
  Nucleic Acids Res. 31, 4847-55 (2003).

• Hassan Javanbakht, Rabih Halwani, Shan Cen, Jenan Saadatmand, Karin Musier-Forsyth, Heinrich Gottlinger, and Lawrence Kleiman
  "The interaction between HIV-1 Gag and human lysyl-tRNA synthetase during viral assembly."
  J. Biol. Chem. 278, 27644-51 (2003).

• Jana Khandogin, Karin Musier-Forsyth, and Darrin M York
  "Insights into the regioselectivity and RNA-binding affinity of HIV-1 nucleocapsid protein from linear-scaling quantum methods."
  J. Mol. Biol. 330, 993-1004 (2003).

• Yasumasa Iwatani, Abbey E Rosen, Jianhui Guo, Karin Musier-Forsyth, and Judith G Levin
  "Efficient initiation of HIV-1 reverse transcription in vitro. Requirement for RNA sequences downstream of the primer binding site abrogated by nucleocapsid protein-dependent primer-template interactions."
  J. Biol. Chem. 278, 14185-95 (2003).

• Minh K Hong, Elizabeth J Harbron, Donald B OConnor, Jianhui Guo, Paul F Barbara, Judith G Levin, and Karin Musier-Forsyth
  "Nucleic acid conformational changes essential for HIV-1 nucleocapsid protein-mediated inhibition of self-priming in minus-strand transfer."
  J. Mol. Biol. 325, 1-10 (2003).

• Shan Cen, Hassan Javanbakht, Sunghoon Kim, Kiyotaka Shiba, Rebecca Craven, Alan Rein, Karla Ewalt, Paul Schimmel, Karin Musier-Forsyth, and Lawrence Kleiman
  "Retrovirus-specific packaging of aminoacyl-tRNA synthetases with cognate primer tRNAs."
  J. Virol. 76, 13111-5 (2002).

• Nilhan Gunasekera, Karin Musier-Forsyth, and Edgar Arriaga
  "Electrophoretic behavior of individual nuclear species as determined by capillary electrophoresis with laser-induced fluorescence detection."
  Electrophoresis 23, 2110-6 (2002).

• Mark C Williams, Robert J Gorelick, and Karin Musier-Forsyth
  "Specific zinc-finger architecture required for HIV-1 nucleocapsid proteins nucleic acid chaperone function."
  Proc. Natl. Acad. Sci. U.S.A. 99, 8614-9 (2002).

• Fai-Chu Wong, Penny J Beuning, Maria Nagan, Kiyotaka Shiba, and Karin Musier-Forsyth
  "Functional role of the prokaryotic proline-tRNA synthetase insertion domain in amino acid editing."
  Biochemistry 41, 7108-15 (2002).

• Hassan Javanbakht, Shan Cen, Karin Musier-Forsyth, and Lawrence Kleiman
  "Correlation between tRNALys3 aminoacylation and its incorporation into HIV-1."
  J. Biol. Chem. 277, 17389-96 (2002).

• Penny J Beuning, Maria C Nagan, Christopher J Cramer, Karin Musier-Forsyth, Josep-Lluis Gelpí, and Donald Bashford
  "Efficient aminoacylation of the tRNAAla acceptor stem dependence on the 271 base pair."
  RNA 8, 659-70 (2002).

• Richard S A Lipman, Penny J Beuning, Karin Musier-Forsyth, and Ya-Ming Hou
  "Amino acid activation of a dual-specificity tRNA synthetase is independent of tRNA."
  J. Mol. Biol. 316, 421-7 (2002).

• M R Hargittai, A T Mangla, R J Gorelick, and K Musier-Forsyth
  "HIV-1 nucleocapsid protein zinc finger structures induce tRNALys,3 structural changes but are not critical for primer/template annealing."
  J. Mol. Biol. 312, 985-97 (2001).

• P J Beuning and K Musier-Forsyth
  "Species-specific differences in amino acid editing by class II prolyl-tRNA synthetase."
  J. Biol. Chem. 276, 30779-85 (2001).

• B Burke, R S Lipman, K Shiba, K Musier-Forsyth, and Y M Hou
  "Divergent adaptation of tRNA recognition by Methanococcus jannaschii prolyl-tRNA synthetase."
  J. Biol. Chem. 276, 20286-91 (2001).

• S Cen, A Khorchid, H Javanbakht, J Gabor, T Stello, K Shiba, K Musier-Forsyth, and L Kleiman
  "Incorporation of lysyl-tRNA synthetase into human immunodeficiency virus type 1."
  J. Virol. 75, 5043-8 (2001).

• M C Williams, I Rouzina, J R Wenner, R J Gorelick, K Musier-Forsyth, and V A Bloomfield
  "Mechanism for nucleic acid chaperone activity of HIV-1 nucleocapsid protein revealed by single molecule stretching."
  Proc. Natl. Acad. Sci. U.S.A. 98, 6121-6 (2001).

• B Burke, F Yang, F Chen, C Stehlin, B Chan, and K Musier-Forsyth
  "Evolutionary coadaptation of the motif 2--acceptor stem interaction in the class II prolyl-tRNA synthetase system."
  Biochemistry 39, 15540-7 (2000).

• M R Hargittai and K Musier-Forsyth
  "Use of terbium as a probe of tRNA tertiary structure and folding."
  RNA 6, 1672-80 (2000).

• P J Beuning and K Musier-Forsyth
  "Hydrolytic editing by a class II aminoacyl-tRNA synthetase."
  Proc. Natl. Acad. Sci. U.S.A. 97, 8916-20 (2000).

• M C Nagan, P Beuning, K Musier-Forsyth, and C J Cramer
  "Importance of discriminator base stacking interactions molecular dynamics analysis of A73 microhelixAla variants."
  Nucleic Acids Res. 28, 2527-34 (2000).

• K Musier-Forsyth and P J Beuning
  "Role of zinc ion in translational accuracy becomes crystal clear."
  Nat. Struct. Biol. 7, 435-6 (2000).