Center for RNA Biology Publications

Publications by Juan Alfonzo since 2000

• Jessica M Wohlgamuth-Benedum, Mary Anne T Rubio, Zdenek Paris, Shaojun Long, Pavel Poliak, Julius Lukes, and Juan D Alfonzo
  "Thiolation Controls Cytoplasmic tRNA Stability and Acts as a Negative Determinant for tRNA Editing in Mitochondria."
  J. Biol. Chem. 284, 23947-53 (2009).

• Juan D Alfonzo and Dieter Söll
  "Mitochondrial tRNA import--the challenge to understand has just begun."
  Biol. Chem. 390, 717-22 (2009).

• Zdenek Paris, Mary Anne T Rubio, Julius Lukes, and Juan D Alfonzo
  "Mitochondrial tRNA import in Trypanosoma brucei is independent of thiolation and the Rieske protein."
  RNA 15, 1398-406 (2009).

• Augusto Simoes-Barbosa, Camila Louly, Octávio L Franco, Mary A Rubio, Juan D Alfonzo, and Patricia J Johnson
  "The divergent eukaryote Trichomonas vaginalis has an m7G cap methyltransferase capable of a single N2 methylation."
  Nucleic Acids Res. 36, 6848-58 (2008).

• Mary Anne T Rubio, Jesse J Rinehart, Bethany Krett, Stéphane Duvezin-Caubet, Andreas S Reichert, Dieter Söll, and Juan D Alfonzo
  "Mammalian mitochondria have the innate ability to import tRNAs by a mechanism distinct from protein import."
  Proc. Natl. Acad. Sci. U.S.A. 105, 9186-91 (2008).

• Kirk W Gaston, Mary Anne T Rubio, and Juan D Alfonzo
  "OXOPAP assay for selective amplification of aminoacylated tRNAs from total cellular fractions."
  Methods 44, 170-5 (2008).

• Jiqiang Ling, Hervé Roy, Daoming Qin, Mary Anne T Rubio, Juan D Alfonzo, Kurt Fredrick, and Michael Ibba
  "Pathogenic mechanism of a human mitochondrial tRNAPhe mutation associated with myoclonic epilepsy with ragged red fibers syndrome."
  Proc. Natl. Acad. Sci. U.S.A. 104, 15299-304 (2007).

• Liliana Torcoroma García, Ney Ribeiro Leite, Juan D Alfonzo, and Otavio Henrique Thiemann
  "Effects of Trypanosoma brucei tryptophanyl-tRNA synthetases silencing by RNA interference."
  Mem. Inst. Oswaldo Cruz 102, 757-62 (2007).

• Mary Anne T Rubio, Irena Pastar, Kirk W Gaston, Frank L Ragone, Christian J Janzen, George A M Cross, F Nina Papavasiliou, and Juan D Alfonzo
  "An adenosine-to-inosine tRNA-editing enzyme that can perform C-to-U deamination of DNA."
  Proc. Natl. Acad. Sci. U.S.A. 104, 7821-6 (2007).

• Monika J Madej, Juan D Alfonzo, and Alexander Hüttenhofer
  "Small ncRNA transcriptome analysis from kinetoplast mitochondria of Leishmania tarentolae."
  Nucleic Acids Res. 35, 1544-54 (2007).

• Kirk W Gaston, Mary Anne T Rubio, Jessica L Spears, Irena Pastar, F Nina Papavasiliou, and Juan D Alfonzo
  "C to U editing at position 32 of the anticodon loop precedes tRNA 5 leader removal in trypanosomatids."
  Nucleic Acids Res. 35, 6740-9 (2007).

• Adam J Yakovich, Frank L Ragone, Juan D Alfonzo, Dan L Sackett, and Karl A Werbovetz
  "Leishmania tarentolae purification and characterization of tubulin and its suitability for antileishmanial drug screening."
  Exp. Parasitol. 114, 289-96 (2006).

• A Cassago, E M Rodrigues, E L Prieto, K W Gaston, J D Alfonzo, M P Iribar, M J Berry, A K Cruz, and O H Thiemann
  "Identification of Leishmania selenoproteins and SECIS element."
  Mol. Biochem. Parasitol. 149, 128-34 (2006).

• Mary Anne T Rubio, Frank L Ragone, Kirk W Gaston, Michael Ibba, and Juan D Alfonzo
  "C to U editing stimulates A to I editing in the anticodon loop of a cytoplasmic threonyl tRNA in Trypanosoma brucei."
  J. Biol. Chem. 281, 115-20 (2006).

• Hervé Roy, Jiqiang Ling, Juan Alfonzo, and Michael Ibba
  "Loss of editing activity during the evolution of mitochondrial phenylalanyl-tRNA synthetase."
  J. Biol. Chem. 280, 38186-92 (2005).

• Jesse Rinehart, Bethany Krett, Mary Anne T Rubio, Juan D Alfonzo, and Dieter Söll
  "Saccharomyces cerevisiae imports the cytosolic pathway for Gln-tRNA synthesis into the mitochondrion."
  Genes Dev. 19, 583-92 (2005).

• Sandro Sbicego, Juan D Alfonzo, Antonio M Estévez, Mary Anne T Rubio, Xuedong Kang, Christoph W Turck, Marian Peris, and Larry Simpson
  "RBP38, a novel RNA-binding protein from trypanosomatid mitochondria, modulates RNA stability."
  Eukaryotic Cell 2, 560-8 (2003).

• Paulo S Monzani, Juan D Alfonzo, Larry Simpson, Glaucius Oliva, and Otavio H Thiemann
  "Cloning, characterization and preliminary crystallographic analysis of Leishmania hypoxanthine-guanine phosphoribosyltransferase."
  Biochim. Biophys. Acta 1598, 3-9 (2002).

• Pamela F Crain, Juan D Alfonzo, Jef Rozenski, Stephen T Kapushoc, James A McCloskey, and Larry Simpson
  "Modification of the universally unmodified uridine-33 in a mitochondria-imported edited tRNA and the role of the anticodon arm structure on editing efficiency."
  RNA 8, 752-61 (2002).

• Stephen T Kapushoc, Juan D Alfonzo, and Larry Simpson
  "Differential localization of nuclear-encoded tRNAs between the cytosol and mitochondrion in Leishmania tarentolae."
  RNA 8, 57-68 (2002).

• R Carrillo, O H Thiemann, J D Alfonzo, and L Simpson
  "Uridine insertion/deletion RNA editing in Leishmania tarentolae mitochondria shows cell cycle dependence."
  Mol. Biochem. Parasitol. 113, 175-81 (2001).

• S T Kapushoc, J D Alfonzo, M A Rubio, and L Simpson
  "End processing precedes mitochondrial importation and editing of tRNAs in Leishmania tarentolae."
  J. Biol. Chem. 275, 37907-14 (2000).

• M A Rubio, X Liu, H Yuzawa, J D Alfonzo, and L Simpson
  "Selective importation of RNA into isolated mitochondria from Leishmania tarentolae."
  RNA 6, 988-1003 (2000).

• L Simpson, O H Thiemann, N J Savill, J D Alfonzo, and D A Maslov
  "Evolution of RNA editing in trypanosome mitochondria."
  Proc. Natl. Acad. Sci. U.S.A. 97, 6986-93 (2000).